Bioactivity | SC-51316 is an oral active angiotensin II receptor antagonist with the IC50 values of 3.6 and 5.1 nM in rat adrenal cortical and rat uterine membrane, respectively. SC-51316 shows antihypertensive activity in vivo and in vitro[1][2]. |
CAS | 133690-62-7 |
Formula | C24H29N7O |
Molar Mass | 431.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Olins GM, et al. In vitro pharmacology of a nonpeptidic angiotensin II receptor antagonist, SC-51316. J Pharmacol Exp Ther. 1992;261(3):1037-1043. [2]. Olins GM, et al. In vivo pharmacology of SC-51316, a nonpeptidic angiotensin II receptor antagonist. Am J Hypertens. 1993;6(7 Pt 1):619-625. |