| Bioactivity | (+)-JJ-74-138, a novel non-competitive androgen receptor (AR) antagonist, is capable of inhibiting Enzalutamide-resistant CRPC[1]. |
| Invitro | (+)-JJ-74-138 是 JJ-450 的一种强效类似物，用于抑制在表达缺乏LBD的雄激素受体剪接变体的细胞系中，雄激素独立的雄激素受体 (AR) 激活[1]。(+)-JJ-74-138可以抑制AR及ARv7靶基因的mRNA表达，并在没有雄激素的情况下降低细胞核中的AR水平[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> (+)-JJ-74-138 相关抗体: |
| CAS | 2135545-34-3 |
| Formula | C22H22F8N2OS |
| Molar Mass | 514.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. (+)-JJ-74-138 is a Novel Noncompetitive Androgen Receptor Antagonist. Mol Cancer Ther. 2022 Apr 1;21(4):483-492. |
(+)-JJ-74-138
CAS: 2135545-34-3 F: C22H22F8N2OS W: 514.48
(+)-JJ-74-138, a novel non-competitive androgen receptor (AR) antagonist, is capable of inhibiting Enzalutamide-resistan
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.