Bioactivity | SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM[1]. |
Name | SB-328437 |
CAS | 247580-43-4 |
Formula | C21H18N2O5 |
Molar Mass | 378.38 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. White JR, et al. Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced eosinophil migration. J Biol Chem. 2000 Nov 24;275(47):36626-31. |