| Bioactivity | PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts[1]. |
| Name | PKUMDL-LC-101-D04 |
| CAS | 2143896-83-5 |
| Formula | C14H23ClN4O2S2 |
| Molar Mass | 378.94 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Li C, et al. Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4. J Med Chem. 2019;62(1):266-275. |
PKUMDL-LC-101-D04
CAS: 2143896-83-5 F: C14H23ClN4O2S2 W: 378.94
PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric acti
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.