Bioactivity | SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction[1]. |
Name | SB 202474 |
CAS | 172747-50-1 |
Formula | C17H17N3O |
Molar Mass | 279.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bellei B, et al. p38 regulates pigmentation via proteasomal degradation of tyrosinase. J Biol Chem. 2010;285(10):7288-7299. |