| Bioactivity | SARS-CoV-2 nsp3-IN-2 is a macrodomain (Mac1) inhibitor with IC50 value of 180 μM. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe and can be used for the research of viral[1]. |
| Target | IC50: 180 μM (Mac1) |
| Invitro | SARS-CoV-2 nsp3-IN-2 emonstrates weak potency against Mac1 in an ADP-ribose binding AlphaScreen assay with IC50 value of 180 μM[1]. |
| Name | SARS-CoV-2 nsp3-IN-2 |
| CAS | 2038858-11-4 |
| Formula | C10H12N4O2 |
| Molar Mass | 220.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lavinia M Sherrill, et al. Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV2 nsp3 Macrodomain. bioRxiv. 2022 Feb 28;2022.02.27.482176. |
SARS-CoV-2 nsp3-IN-2
CAS: 2038858-11-4 F: C10H12N4O2 W: 220.23
SARS-CoV-2 nsp3-IN-2 is a macrodomain (Mac1)inhibitor with IC50 value of 180 μM. SARS-CoV-2 nsp3-IN-2 is a small molecu
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