| Bioactivity | SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 value of 11 nM. Additionally, SARS-CoV-2 Mpro-IN-31 effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively[1]. |
| Target | IC50: 11 nM (SARS-CoV-2 MPro). IC50: 24 nM (cathepsin B). IC50: 1.8 nM (cathepsin L). |
| CAS | 870153-73-4 |
| Formula | C31H34Cl2N4O7 |
| Molar Mass | 645.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Poli A N R, et al. Design of novel and highly selective SARS-CoV-2 main protease inhibitors[J]. Antimicrobial Agents and Chemotherapy, 2024, 68(10): e00562-24. |
SARS-CoV-2 Mpro-IN-31
CAS: 870153-73-4 F: C31H34Cl2N4O7 W: 645.53
SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 value of 11 nM. Additionally, SARS-C
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