| Bioactivity | SARS-CoV-2 3CLpro-IN-9, an aldehyde, is a broad-spectrum cyclopropane-based inhibitor of coronavirus 3C-like proteases (3CLpro). SARS-CoV-2 3CLpro-IN-9 inhibits SARS-CoV-2, SARS-CoV-1 and MERS-CoV 3CLpro with IC50 values of 140 nM, 350 nM, 120 nM, respectively. SARS-CoV-2 3CLpro-IN-9 inhibits SARS-CoV-2 replication with an IC50 value of 11 nM[1]. |
| Invitro | SARS-CoV-2 3CLpro-IN-9 (化合物 11c) 在融合细胞中的 CC50 为 >100 μM[1]。 |
| Name | SARS-CoV-2 3CLpro-IN-9 |
| Formula | C25H35N3O6 |
| Molar Mass | 473.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chamandi S Dampalla, et al. Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. ACS Pharmacol Transl Sci. 2022 Dec 28;6(1):181-194. |
SARS-CoV-2 3CLpro-IN-9
CAS: F: C25H35N3O6 W: 473.56
SARS-CoV-2 3CLpro-IN-9, an aldehyde, is a broad-spectrum cyclopropane-based inhibitor of coronavirus 3C-like proteases (
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.