| Bioactivity | Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positive bacteria[1]. |
| Invitro | Antibacterial agent 123 (compound 111) shows excellent activity (MICS. aureus strains[1]. |
| In Vivo | Antibacterial agent 123 (compound 111) (p.o. (10 mg/kg) and i.v. (0.5 mg/kg); once) exhibits favorable pharmacokinetics profiles[1]. Animal Model: |
| Name | Antibacterial agent 123 |
| CAS | 2615254-55-0 |
| Formula | C17H8F9N3O |
| Molar Mass | 441.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Schultz JR, et al. Identification of 5-(Aryl/Heteroaryl)amino-4-quinolones as Potent Membrane-Disrupting Agents to Combat Antibiotic-Resistant Gram-Positive Bacteria. J Med Chem. 2022 Oct 11. |
Antibacterial agent 123
CAS: 2615254-55-0 F: C17H8F9N3O W: 441.25
Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positiv
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