| Bioactivity | S2-16 is a synthetic peptide from the S2 region of cardiac myosin. S2-16 is a cryptic epitope that induces myocarditis in Lewis rats. A cryptic epitope is an epitope that is not recognized by antibodies or T cells after the animal is immunized with the intact antigen. S2-16 can be used to study the mechanism of autoimmune myocarditis[1]. |
| CAS | 672333-56-1 |
| Sequence | Lys-Arg-Lys-Leu-Glu-Gly-Asp-Leu-Lys-Leu-Thr-Gln-Glu-Ser-Ile-Met-Asp-Leu-Glu-Asn- |
| Shortening | KRKLEGDLKLTQESIMDLENDKQQL |
| Formula | C126H218N36O44S |
| Molar Mass | 2973.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li Y, et al. Cryptic epitope identified in rat and human cardiac myosin S2 region induces myocarditis in the Lewis rat[J]. The Journal of Immunology, 2004, 172(5): 3225-3234. |
S2-16
CAS: 672333-56-1 F: C126H218N36O44S W: 2973.36
S2-16 is a synthetic peptide from the S2 region of cardiac myosin. S2-16 is a cryptic epitope that induces myocarditis i
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