| Bioactivity | S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively[1]. | ||||||||||||
| Target | Ki: 243 μM (Schizosaccharomyces pombe lumazine synthase); 9.6 μM (Mycobacterium tuberculosis lumazine synthase) | ||||||||||||
| Invitro | S.pombe lumazine synthase-IN-1 (Compound 21) is a class II compound with OCH3 groups displays slightly better potencies than its counterparts with OH groups[1]. | ||||||||||||
| Name | S.pombe lumazine synthase-IN-1 | ||||||||||||
| CAS | 331726-35-3 | ||||||||||||
| Formula | C14H13N3O6 | ||||||||||||
| Molar Mass | 319.27 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Arindam Talukdar, et al. Discovery and Development of a Small Molecule Library With Lumazine Synthase Inhibitory Activity. J Org Chem. 2009 Aug 7;74(15):5123-34. |
S.pombe lumazine synthase-IN-1
CAS: 331726-35-3 F: C14H13N3O6 W: 319.27
S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosac
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