| Bioactivity | S-WJM992 (compound 10ahb) is an antiparasitic agent that inhibits ATPase activity under high [Na+] conditions. S-WJM992 also has significant inhibitory effects on parasites that have developed PfATP4 inhibitor-resistance. S-WJM992 is a potential transmission blocker that effectively inhibits gamete development and prevents parasite transmission to mosquitoes via blood feeding[1]. |
| Target | Na+/K+ ATPase |
| Formula | C22H18ClFN6O3 |
| Molar Mass | 468.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4 |