| Bioactivity | RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity[1]. |
| Target | Ryanodine receptor |
| Name | RyRs activator 3 |
| CAS | 2850333-35-4 |
| Formula | C23H19BrCl2N6O3 |
| Molar Mass | 578.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pang X, et al. Design, Synthesis, and Insecticidal Evaluation of N-Pyridylpyrazole Amide Derivatives Containing 4,5-Dihydroisoxazole Amide as Potential Ryanodine Receptor Activators. J Agric Food Chem. 2023 Sep 20;71(37):13688-13695. . |