Rp-8-Br-cGMPS

CAS: 150418-07-8 F: C10H11BrN5O6PS W: 440.17

Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. Rp-8-Br-cGMPS is also an agonist o

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Bioactivity	Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. Rp-8-Br-cGMPS is also an agonist of the rod CNG channel and an inhibitor of PKG. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca2+ reduction by activating Ca2+-ATPase and subsequently removing Ca2+ from the cell[1][2].
CAS	150418-07-8
Formula	C10H11BrN5O6PS
Molar Mass	440.17
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Rashatwar SS, et, al. Effects of 8-bromo-cGMP on Ca2+ levels in vascular smooth muscle cells: possible regulation of Ca2+-ATPase by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5685-9. [2]. Barnstable CJ, et al. Modulation of synaptic function by cGMP and cGMP-gated cation channels. Neurochem Int. 2004 Nov;45(6):875-84.