| Bioactivity | Ro19-4603 is a benzodiazepine inverse agonist. Ro19-4603 antagonizes ethanol (EtOH) intake in alcohol-preferring rats[1]. |
| In Vivo | Ro19-4603 (0-0.3 mg/kg，腹腔注射) 显着降低嗜酒大鼠在 8 小时间隔内的乙醇摄入量[1]。 Animal Model: |
| Name | Ro19-4603 |
| CAS | 99632-94-7 |
| Formula | C15H17N3O3S |
| Molar Mass | 319.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. June HL, et al. The benzodiazepine inverse agonist RO19-4603 exerts prolonged and selective suppression of ethanol intake in alcohol-preferring (P) rats. Psychopharmacology (Berl). 1994 Jul;115(3):325-31. |