| Bioactivity | Ro 64-5229 is a selective, non-competitive mGlu2 antagonist. RO 64-5229 reduces the presynaptic inhibitory effect of Neuroligin 1[1]. |
| Target | mGlu2. |
| Invitro | RO 64-5229 (50 µM) 降低神经连接蛋白 1 的突触前抑制作用[1]。 |
| Name | Ro 64-5229 |
| CAS | 246852-46-0 |
| Formula | C17H19Cl2N3O |
| Molar Mass | 352.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gjørlund MD, et al. Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2. Front Mol Neurosci. 2017 May 3;10:116. |
Ro 64-5229
CAS: 246852-46-0 F: C17H19Cl2N3O W: 352.26
Ro 64-5229 is a selective, non-competitive mGlu2 antagonist. RO 64-5229 reduces the presynaptic inhibitory effect of Neu
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