| Bioactivity | Ro 18-3981 is a dihydropyridine that inhibits cardiac Ca2+ channels. Ro 18-3981 shows higher inhibitory activity when the cell membrane is in a depolarized state (Vh=-20 mV: IC50=2.3 nM; Vh=-50 mV: IC50=100 nM)[1]. |
| CAS | 103295-92-7 |
| Formula | C24H33N3O8S |
| Molar Mass | 523.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Holck M, et al. Inhibition of myocardial Ca2+ channels by three dihydropyridines with different structural features: potential‐dependent blockade by Ro 18–3981[J]. British journal of pharmacology, 1987, 91(1): 61-67. |
Ro 18-3981
CAS: 103295-92-7 F: C24H33N3O8S W: 523.60
Ro 18-3981 is a dihydropyridine that inhibits cardiac Ca2+ channels. Ro 18-3981 shows higher inhibitory activity when th
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