Bioactivity | PI3Kα-IN-24 (WR23) is a PI3Kα inhibitor with an IC50 of 0.025 μM and exhibits a significant pAktSer473 suppression effect. PI3Kα-IN-24 can be utilized in cancer research[1]. |
CAS | 1350960-66-5 |
Formula | C19H18BrN3O3S |
Molar Mass | 448.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wu P, et al. Discovery of novel 2-piperidinol-3-(arylsulfonyl)quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors. Bioorg Med Chem. 2012 May 1;20(9):2837-44. |