| Bioactivity | Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal[1][2]. | ||||||||||||
| Name | Reproxalap | ||||||||||||
| CAS | 916056-79-6 | ||||||||||||
| Formula | C12H13ClN2O | ||||||||||||
| Molar Mass | 236.70 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Susan Macdonald, et al. ADX-102, a novel aldehyde trap, reduces nociceptive behavior in mouse models of carrageenan and CFA induced pain. [2]. Reproxalap Phase 2b Dry Eye Disease Results. |