PeptideDB

Reproxalap

CAS: 916056-79-6 F: C12H13ClN2O W: 236.70

Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal[1][2].
Name Reproxalap
CAS 916056-79-6
Formula C12H13ClN2O
Molar Mass 236.70
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Susan Macdonald, et al. ADX-102, a novel aldehyde trap, reduces nociceptive behavior in mouse models of carrageenan and CFA induced pain. [2]. Reproxalap Phase 2b Dry Eye Disease Results.