| Bioactivity | Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice[1]. | ||||||||||||
| Name | Acid Ceramidase-IN-1 | ||||||||||||
| CAS | 2415225-30-6 | ||||||||||||
| Formula | C18H25N3O3 | ||||||||||||
| Molar Mass | 331.41 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664. |
Acid Ceramidase-IN-1
CAS: 2415225-30-6 F: C18H25N3O3 W: 331.41
Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid
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