| Bioactivity | Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4[1]. |
| CAS | 835621-12-0 |
| Formula | C20H13ClF4N4O4 |
| Molar Mass | 484.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ying-Hui Li, et al. Functional characterization of 27 CYP3A4 protein variants to metabolize regorafenib in vitro. Basic Clin Pharmacol Toxicol. 2019 Oct;125(4):337-344. |
Regorafenib N-oxide and N-desmethyl (M5)
CAS: 835621-12-0 F: C20H13ClF4N4O4 W: 484.79
Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-1020
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