Bioactivity | RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a Ki of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research[1]. |
Invitro | RasGRP3 ligand 1 (1-10000 nM, 30 min) 在过表达 RasGRP 的 HEK293、LNCaP 和 Ramos 细胞中剂量依赖性地激活 Ras[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> RasGRP3 ligand 1 相关抗体: |
CAS | 2229068-13-5 |
Formula | C21H25NO5 |
Molar Mass | 371.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ann J, et al. α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands. J Med Chem. 2018 Jul 26;61(14):6261-6276. |