Bioactivity | Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively[1]. |
Target | Ki: 5.15±0.39 nM (GABA(-) ligand), 6.11±0.26 nM (GABA(+) ligand) |
Name | Radequinil |
CAS | 219846-31-8 |
Formula | C18H14N4O3 |
Molar Mass | 334.33 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. Hashimoto T, et al. Pharmacological properties of AC-3933, a novel benzodiazepine receptor partial inverse agonist. Neuroscience. 2014 Jan 3;256:352-9. |