| Bioactivity | RSRGVFF (FOXP3 inhibitor P60) is a mixed-type angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, boasting an IC50 value of 5.01 μM[1]. RSRGVFF is capable of binding to both active and non-active sites of ACE and its substrate HHL complex, thus reducing the catalytic activity of ACE. RSRGVFF can be further utilized for research on lowering hypertension[1]. |
| Target | IC50: 5.01 μM (ACE). |
| Sequence | Arg-Ser-Arg-Gly-Val-Phe-Phe |
| Shortening | RSRGVFF |
| Formula | C40H61N13O9 |
| Molar Mass | 867.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lin Z, et al. Screening, ACE-inhibitory mechanism and structure-activity relationship of a novel ACE-inhibitory peptide from Lepidium meyenii (Maca) protein hydrolysate[J]. Food Bioscience, 2023, 52: 102374. |