| Bioactivity | RR-RJW100, the enantiomer of RJW100, is an nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1) agonist. RJW100 can be synthesized as two enantiomers, RR-RJW100 and SS-RJW100, with RR-RJW100 shown to be the more potent LRH-1 agonist. RR-RJW100 is involved in the regulation of metabolic homeostasis and is used in studies of diabetes, liver disease and inflammatory bowel disease[1][2]. | ||||||||||||
| Name | RR-RJW100 | ||||||||||||
| Formula | C28H34O | ||||||||||||
| Molar Mass | 386.57 | ||||||||||||
| Appearance | Viscous liquid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Suzanne G Mays, et al. Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist. Sci Rep. 2020 Dec 17;10(1):22279. [2]. Alisa Lang, et al. The Medicinal Chemistry and Therapeutic Potential of LRH-1 Modulators. J Med Chem. 2021 Dec 9;64(23):16956-16973. |