| Bioactivity | ROCK-IN-10 (compound 50) is a potent ROCK inhibitor with IC50 values of 6 nM and 4 nM for ROCK1 and ROCK2, respectively. ROCK-IN-10 shows >100-fold selectivity against other kinases[1]. |
| CAS | 1038549-25-5 |
| Formula | C25H25N5O3 |
| Molar Mass | 443.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tina Morwick, et al. Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase. J Med Chem. 2010 Jan 28;53(2):759-77. |
ROCK-IN-10
CAS: 1038549-25-5 F: C25H25N5O3 W: 443.50
ROCK-IN-10 (compound 50) is a potent ROCK inhibitor with IC50 values of 6 nM and 4 nM for ROCK1 and ROCK2, respectively.
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