| Bioactivity | RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses. |
| Invitro | RO-7 is a compound that potently inhibits influenza virus replication and belongs to a new class of drugs in late-stage clinical trials for treatment of influenza virus infection. RO-7 displays broad-spectrum anti-influenza activity in vitro and protects mice from lethal challenge with both influenza A and B viruses[1]. |
| In Vivo | RO-7 protects mice from lethal challenge with both influenza A and B viruses[1]. |
| Name | RO-7 |
| CAS | 1370241-45-4 |
| Formula | C24H20F3N3O3S |
| Molar Mass | 487.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jones JC, et al. Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation InfluenzaVirus Endonuclease Inhibitors. MBio. 2018 Apr 24;9(2). pii: e00430-18. |