Bioactivity | RNase L-IN-1 (compound 17a) is an inhibitor of RNase L, or Ribonuclease L. RNase L degrades RNAs to prevent viral replication, and mediates the innate immune responses and inflammation[1]. |
Target | RNase L |
Name | RNase L-IN-1 |
Formula | C27H35FN6O3S |
Molar Mass | 542.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hwang J, et al. Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. Eur J Med Chem. 2023 Aug 5;256:115439. |