| Bioactivity | MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1]. |
| Target | 5-α-reductase I |
| Invitro | MK 386（5 μM；48 小时）可调节 LNCaP 细胞中相关基因的 mRNA 水平[1]。 |
| Name | MK 386 |
| CAS | 158493-17-5 |
| Formula | C28H49NO |
| Molar Mass | 415.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84(2):203-11. |