Bioactivity | RG100204 is an orally active AQP9 inhibitor with anti-inflammatory activity. RG100204 can alleviate sepsis-induced cardiac dysfunction (both systolic and diastolic), improve renal dysfunction, and reduce the elevation of LDH, a marker of cellular injury[1]. |
CAS | 2140901-88-6 |
Formula | C20H26N6O2S2 |
Molar Mass | 446.59 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mohammad S, et al. RG100204, a novel Aquaporin-9 inhibitor, reduces septic cardiomyopathy and multiple organ failure in murine sepsis[J]. Frontiers in Immunology, 2022, 13: 900906. |