Bioactivity | RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide,serves as a fluorescent substrate for BACE1(Em=360nm,Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1]. |
Name | RE(EDANS)EVNLDAEFK(DABCYL)R |
CAS | 310427-94-2 |
Sequence | Arg-{Glu(EDANS)}-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(DABCYL)}-Arg |
Shortening | R-{Glu(EDANS)}-EVNLDAEF-{Lys(DABCYL)}-R |
Formula | C91H129N25O25S |
Molar Mass | 2005.22 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ortega A, et.al. Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2183-7. |