| Bioactivity | RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase[1]. | ||||||||||||
| Invitro | RDR 02308 (0-10 μM; 1 h) 在 RAW264.7 细胞中抑制 LPS (HY-D1056) 介导的 IL-6 产生[1]。 Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | RDR 02308 | ||||||||||||
| CAS | 4155-82-2 | ||||||||||||
| Formula | C19H15N3O3 | ||||||||||||
| Molar Mass | 333.34 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lee HK, et al. Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors. Mol Pharmacol. 2007 Oct;72(4):868-75. |