| Bioactivity | R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase[1]. |
| Invitro | R8-T198wt peptide (KD=323 nM) shows significant affinity for Pim-1. R8-T198wt peptide inhibits p27Kip1 phosphorylation by Pim-1 in cells[1].R8-T198wt peptide induces G1 arrest and apoptosis in DU145 cells[1].R8-T198wt treatment also enhances the HA-p27Kip1 expression level[1]. |
| Name | R8-T198wt |
| CAS | 2305815-72-7 |
| Shortening | GGGRRRRRRRRGCKKPGLRRRQT |
| Formula | C111H211N59O26S |
| Molar Mass | 2820.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
R8-T198wt
CAS: 2305815-72-7 F: C111H211N59O26S W: 2820.33
R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
Data collection：peptidedb@qq.com
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