| Bioactivity | CKLF1-C19 is the C-terminal peptide of human chemokine-like factor 1 (CKLF1). CKLF1-C19 interacts with CCR4, and inhibits chemotaxis induced by both CKLF1 and CCL17. CKLF1-C19 can suppress allergic lung inflammation via inhibiting chemotaxis mediated by CCR3 and CCR4[1]. |
| Invitro | CKLF1-C19 (200 ng/mL 或 500 ng/mL; 30 分钟) 诱导人类 Th2 细胞的趋化迁移[1]。CKLF1-C19 (100 ng/mL; 30 分钟) 抑制 CCL-11 诱导的小鼠嗜酸性粒细胞和人 CCR3 转染或小鼠 CCR3 转染的 HEK293 细胞的趋化性[1]。 |
| Name | CKLF1-C19 |
| CAS | 960358-79-6 |
| Shortening | FNPSGPYQKKPVHEKKEVL |
| Formula | C103H161N27O28 |
| Molar Mass | 2225.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
CKLF1-C19
CAS: 960358-79-6 F: C103H161N27O28 W: 2225.54
CKLF1-C19 is the C-terminal peptide of human chemokine-like factor 1 (CKLF1). CKLF1-C19 interacts with CCR4, and inhibit
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