Bioactivity | R715 is a selective bradykinin B1 receptor antagonist. R715 significantly attenuates the hyperalgesic effect developed in Streptozotocin(HY-13753)-diabetic mice[1]. |
Name | R715 |
CAS | 185052-09-9 |
Sequence | Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-{d-βNal}-Ile |
Shortening | Ac-KRPPGFS-{d-βNal}-I |
Formula | C57H81N13O12 |
Molar Mass | 1140.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gabra BH, et al. Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice. Peptides. 2003;24(8):1131-1139. |