| Bioactivity | IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1]. |
| Target | Ki: 6-11 nM (endothelin B receptors), 0.4-0.7 μM (endothelin A receptors) |
| Name | IRL 1038 |
| CAS | 144602-02-8 |
| Sequence | Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge:Cys1-Cys5) |
| Shortening | CVYFCHLDIIW (Disulfide bridge:Cys1-Cys5) |
| Formula | C68H92N14O15S2 |
| Molar Mass | 1409.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Urade Y, et al. An endothelin B receptor-selective antagonist: IRL 1038, [Cys11-Cys15]-endothelin-1(11-21). FEBS Lett. 1992 Oct 12;311(1):12-6. doi: 10.1016/0014-5793(92)81355-p. |