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Quinolinic acid-13C7

CAS: 1346642-91-8 F: 13C7H5NO4 W: 174.07

Quinolinic acid-13C7is the 13C labeledQuinolinic acid(HY-100807). Quinolinic acid is an endogenous N-methyl-D-aspartate
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Quinolinic acid-13C7is the 13C labeledQuinolinic acid(HY-100807)[1]. Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction[2][3].
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
Name Quinolinic acid-13C7
CAS 1346642-91-8
Formula 13C7H5NO4
Molar Mass 174.07
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.