| Bioactivity | QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress[1]. |
| Invitro | QM295（25 μM，50 μM）在动力学测定中抑制 AUR 荧光的发展，IC50 值为 1.9 μM[1]。 |
| In Vivo | QM295 (50 μM, 30 min) 在体内积累了迁移率较低的 ERO1α形式[1]。 |
| Name | QM295 |
| CAS | 1241046-32-1 |
| Formula | C17H13NO4 |
| Molar Mass | 295.29 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Jaime D Blais, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2;285(27):20993-1003. |