| Bioactivity | ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1]. |
| Target | IC50: 0.019 µM (ATX) |
| Invitro | ATX inhibitor 17 (compound 25a) (0-15 µM; 72 h) shows excellent anti-proliferative activities in breast cancer cells[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | ATX inhibitor 17 |
| CAS | 2750152-64-6 |
| Formula | C29H29F5N8S |
| Molar Mass | 616.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lei H,et al. Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects. Eur J Med Chem. 2020 Sep 1;201:112456. |