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ATX inhibitor 17

CAS: 2750152-64-6 F: C29H29F5N8S W: 616.65

ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferativ
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Bioactivity ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1].
Target IC50: 0.019 µM (ATX)
Invitro ATX inhibitor 17 (compound 25a) (0-15 µM; 72 h) shows excellent anti-proliferative activities in breast cancer cells[1]. Cell Cytotoxicity Assay[1] Cell Line:
Name ATX inhibitor 17
CAS 2750152-64-6
Formula C29H29F5N8S
Molar Mass 616.65
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Lei H,et al. Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects. Eur J Med Chem. 2020 Sep 1;201:112456.