Bioactivity | Prochlorperazine dimaleate is a first-generation antipsychotic. Prochlorperazine dimaleate can be used in the research of chemotherapy-induced nausea and vomiting (CINV). Prochlorperazine dimaleate also possesses anticancer activity. Prochlorperazine dimaleate exhibits IC50 values of 6.4 μM, 4.5 μM and 2.3 μM for NOX1, NOX2 and NOX5, respectively[1][2]. |
CAS | 84-02-6 |
Formula | C28H32ClN3O8S |
Molar Mass | 606.09 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Reference | [1]. Melissa Lau Moon Lin, et al. The Safety of Prochlorperazine in Children: A Systematic Review and Meta-Analysis. Drug Saf. 2016 Jun;39(6):509-16. [2]. Michał Otręba, et al. In vitro anticancer activity of fluphenazine, perphenazine and prochlorperazine. A review. J Appl Toxicol. 2021 Jan;41(1):82-94. |