Bioactivity | 2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc is the PD-L1 ligand-linker conjugate part of AUTAC PD-L1 degrader-3 (HY-169363). 2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc can be utilized in AUTAC synthesis[1]. |
Formula | C35H45N5O6 |
Molar Mass | 631.76 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang K, et al. Discovery of small molecules for autophagy-lysosome degradation of immune checkpoint proteins. Eur J Med Chem. 2024 Dec 15;280:116958. |