| Bioactivity | Pomstafib-2 is a potent and selective STAT5b inhibitor. Pomstafib-2 decreases the expression of pSTAT5b and induces Apoptosis[1][2]. |
| Invitro | Pomstafib-2 (compound 8) (0-10 µM; 4 h) decreases the expression of pSTAT5b in a dose-dependent manner in STAT5b-GFP-transfected K562 cells[1].Pomstafib-2 (0, 10, 20, 40, 60, 80 µM; 48 h) induces apoptosis in a dose-dependent manner in STAT5-dependent K562 cells[1]. Western Blot Analysis[1] Cell Line: |
| Name | Pomstafib-2 |
| CAS | 2332841-83-3 |
| Formula | C52H66N2O20P2 |
| Molar Mass | 1101.03 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Pomstafib-2
CAS: 2332841-83-3 F: C52H66N2O20P2 W: 1101.03
Pomstafib-2 is a potent and selective STAT5b inhibitor. Pomstafib-2 decreases the expression of pSTAT5b and induces Apop
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