| Bioactivity | Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1]. |
| Name | Pomalidomide-PEG1-NH2 hydrochloride |
| CAS | 2380273-67-4 |
| Formula | C17H19ClN4O6 |
| Molar Mass | 410.81 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Lee B, et al. Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug. J Enzyme Inhib Med Chem. 2023 Dec;38(1):51-66. |
Pomalidomide-PEG1-NH2 hydrochloride
CAS: 2380273-67-4 F: C17H19ClN4O6 W: 410.81
Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomal
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