PeptideDB

Polymyxin B2

CAS: 34503-87-2 F: C55H96N16O13 W: 1189.45

Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. P
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains[1].
CAS 34503-87-2
Formula C55H96N16O13
Molar Mass 1189.45
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Meng M, et al. Simultaneous quantitation of polymyxin B1, polymyxin B2 and polymyxin B1-1 in human plasma and treated human urine using solid phase extraction and liquid chromatography–tandem mass spectrometry[J]. Journal of Chromatography B, 2016, 1012: 23-36.