| Bioactivity | Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research[1]. |
| Sequence | Ala-Ala-Ala-Asp-Ala-Ala-Ala-Ala-Leu |
| Shortening | AAADAAAAL |
| Formula | C31H53N9O12 |
| Molar Mass | 743.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Radaev S, et al. Recognition of IgG by Fcγ receptor: the role of Fc glycosylation and the binding of peptide inhibitors[J]. Journal of Biological Chemistry, 2001, 276(19): 16478-16483. |