| Bioactivity | Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist[1]. Piperazine citrate is a vital building block and is an essential core in numerous marketed drugs with diverse pharmacological activities[2]. |
| Invitro | Piperazine citrate is a promising scaffold with analgesic and anti-inflammatory potential[3].Piperazine citrate is a key substructure for antidepressants[4]. |
| Name | Piperazine citrate |
| CAS | 144-29-6 |
| Formula | C6H8O7.3/2 C4H10N2 |
| Molar Mass | 321.33 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Lovell RA. Ivermectin and piperazine toxicoses in dogs and cats. Vet Clin North Am Small Anim Pract. 1990;20(2):453-468. [2]. Girase PS, et al. An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review. Eur J Med Chem. 2021;210:112967. [3]. Jain A, et al. Piperazine: A Promising Scaffold with Analgesic and Anti-inflammatory Potential. Drug Res (Stuttg). 2021;71(2):62-72. [4]. Kumar RR, et al. Piperazine, a Key Substructure for Antidepressants: Its Role in Developments and Structure-Activity Relationships. ChemMedChem. 2021;16(12):1878-1901. |
Piperazine citrate
CAS: 144-29-6 F: C6H8O7.3/2 C4H10N2 W: 321.33
Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist. Piperazine citrate is a vital bui
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