| Bioactivity | 2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity[1]. |
| Invitro | 2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2'-Deoxy-5'-O-DMT-2'-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM[1]. |
| Name | 2'-Deoxy-5'-O-DMT-2'-fluorouridine |
| CAS | 146954-74-7 |
| Formula | C30H29FN2O7 |
| Molar Mass | 548.56 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Christopher McGuigan, et al. Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues. ChemistryOpen. 2016 Jan 21;5(3):227-35. |
2'-Deoxy-5'-O-DMT-2'-fluorouridine
CAS: 146954-74-7 F: C30H29FN2O7 W: 548.56
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fev
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