| Bioactivity | Pim-1 kinase inhibitor 10 (compound 13a) is a both competitive and non-competitive inhibitor of PIM-1/2 kinase. Pim-1 kinase inhibitor 10 can induce cell apoptosis and exhibits anticancer activity. Pim-1 kinase inhibitor 10 also induces caspase 3/7 activation[1]. |
| Name | Pim-1 kinase inhibitor 10 |
| CAS | 2918764-57-3 |
| Formula | C21H13N3O3 |
| Molar Mass | 355.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. El-Miligy MMM, et, al. Discovery of new pyridine-quinoline hybrids as competitive and non-competitive PIM-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2152810. |
Pim-1 kinase inhibitor 10
CAS: 2918764-57-3 F: C21H13N3O3 W: 355.35
Pim-1 kinase inhibitor 10 (compound 13a) is a both competitive and non-competitive inhibitor of PIM-1/2 kinase. Pim-1 ki
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