| Bioactivity | Pep2-8 is a PCSK9 inhibitor with a binding KD of 0.7 μM and an IC50 of 1.4 μM[1]. | ||||||
| Invitro | Pep2-8 binds to C-terminally truncated PCSK9[1].Pep2-8 restored LDL uptake of PCSK9-treated HepG2 cells to about 90% of control activity at a concentration of 50 μM[1]. Cell Viability Assay[1] Cell Line: | ||||||
| Name | Pep2-8 | ||||||
| CAS | 1541011-97-5 | ||||||
| Shortening | Ac-TVFTSWEEYLDWV-NH2 | ||||||
| Formula | C83H110N16O24 | ||||||
| Molar Mass | 1715.85 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |