| Bioactivity | C-Type Natriuretic Peptide (CNP) (1-22), human (TFA),a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor[1][2][3]. | ||||||
| Invitro | C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) (0.01, 0.1, 1, 10, 100, 1000 nM) increases cGMP production in CHO cells expressing human NPR-B in a concentration-dependent manner[1]. | ||||||
| Name | C-Type Natriuretic Peptide (CNP) (1-22), human TFA | ||||||
| CAS | 1966153-17-2 | ||||||
| Shortening | GLSKGCFGLKLDRIGSMSGLGC (Disulfide bridge: Cys6-Cys22) | ||||||
| Formula | C95H158F3N27O30S3 | ||||||
| Molar Mass | 2311.62 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |